Hochschule Reutlingen
Dr. Simon Heine

Dr. Simon Heine

Wissenschaftlicher Mitarbeiter

+49 7121 271 1441

simon.heine@reutlingen-university.de

Gebäude 2, Raum 008

  • MicroLungDetect

Since 06/2014

PhD student at the Margarete Fischer-Bosch Institute of Clinical Pharmacology Stuttgart and University of Tübingen
 “Role of aberrant Cyclin D1-CDK4 activity apart from cell cycle in Mantle Cell Lymphoma and consequences for novel treatment options”

09/2011 – 11/2014

Pharmaceutical Biotechnology (M. Sc.), University of Applied Sciences Jena
Master thesis: “Role of aberrant Cyclin D1-CDK4 activity apart from cell cycle in Mantle Cell Lymphoma and consequences for novel treatment options” at the Institute of Cell Biology and Immunology of the University of Stuttgart

03/2008 – 08/2011

Pharmaceutical Biotechnology (B. Sc.), University of Applied Sciences Biberach
Bachelor thesis: “Establishing a production process on the basis of HEK293 suspension cells” at U3 Pharma GmbH München

  • Nellinger, S., Mrsic, I., Keller, S., Heine, S., Southan, A., Bach, M., Volz, A.-C., Chassé, T., & Kluger, P. J. (2022). Cell-derived and enzyme-based decellularized extracellular matrix exhibit compositional and structural differences that are relevant for its use as a biomaterial. Biotechnology and Bioengineering, 1– 15. https://doi.org/10.1002/bit.28047
  • Wollschlaeger JO, Maatz R, Albrecht FB, Klatt A, Heine S, Blaeser A, Kluger PJ. Scaffolds for Cultured Meat on the Basis of Polysaccharide Hydrogels Enriched with Plant-Based Proteins. Gels. 2022; 8(2):94. https://doi.org/10.3390/gels8020094
  • Heine, Simon; Kleih, Markus; Giménez, Neus; Böpple, Kathrin; Ott, German; Colomer, Dolors et al. (2018): Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA. In: Journal of hematology & oncology 11 (1), S. 112. DOI: 10.1186/s13045-018-0657-6 .
  • Höring, Elisabeth; Montraveta, Arnau; Heine, Simon; Kleih, Markus; Schaaf, Lea; Vöhringer, Matthias C. et al. (2017): Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma. In: British journal of haematology 177 (4), S. 557–561. DOI: 10.1111/bjh.14571 .
  • Schaaf, Lea; Schwab, Matthias; Ulmer, Christoph; Heine, Simon; Mürdter, Thomas E.; Schmid, Jens O. et al. (2016): Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest. In: Cancer research 76 (10), S. 2868–2875. DOI: 10.1158/0008-5472.CAN-15-2908